side effects from clomid on visual Ovarian Hyperstimulation Syndrome

side effects from clomidFirst side effects from clomid is we must be know that patients should be advised that blurring or other visual symptoms such as spots or flashes (scintillating and flashing lights, scotomata) may occasionally occur during treatment with Clomid. These side effects from clomid with visual symptoms increase in the incidence of the increasing size of the dose or duration of treatment and usually disappear within a few days or weeks after Clomid is discontinued. Patients should be warned that these visual symptoms may do activities such as driving a car or operating machinery more hazardous than usual, particularly under conditions of variable lighting.

side effects from clomid may blurring or other visual symptoms

These visual symptoms appear to be due to intensification and prolongation of afterimages. Symptoms often first appear or identified with exposure to a well-lit environment. Although measuring visual acuity was generally not affected, a patient of the study, taking 200 mg of Clomid daily developed blurred vision in 7 days of treatment, which progressed to a severe deterioration of visual acuity of 10 days. No other abnormalities were found, and visual acuity returned to normal on the third day after treatment was stopped.
Ophthalmic definable scotomata and function of cells in the retina (electroretinographic) changes have also been reported. One patient treated during clinical studies developed phosphenes and scotomata during prolonged administration Clomid, who disappeared on day 32 after discontinuation of treatment. Postmarketing surveillance of adverse events has also revealed other visual signs and symptoms while taking Clomid (side effects from clomid).
Although the etiology of these visual symptoms is not yet understood, patients with visual symptoms should discontinue treatment and have a complete ophthalmological evaluation carried out in a hurry.


Ovarian Hyperstimulation Syndrome is more side effects from clomid

OHSS occurred following cyclic use of the therapy, clomiphene citrate or when clomiphene citrate was used in combination with gonadotropins. Transient abnormalities suggestive of liver dysfunction, which may be accompanied by morphological changes in liver biopsy, have been reported in association with ovarian hyperstimulation syndrome (OHSS).


SHO is a different case from uncomplicated ovarian enlargement. Clinical signs of this syndrome in severe cases can include gross ovarian enlargement, gastrointestinal symptoms, ascites, dyspnea, oliguria, and pleural effusion. In addition, the following symptoms have been reported in association with this syndrome: pericardial effusion, anasarca, hydrothorax, acute abdomen, hypotension, renal failure, pulmonary edema, intraperitoneal and ovarian hemorrhage, deep vein thrombosis ovarian torsion and acute respiratory failure . Warning signs of OHSS are abdominal pain, bloating, nausea, vomiting, diarrhea and weight gain. Elevated levels of urinary steroids, different degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. Death due to hypovolemic shock, hemoconcentration, or thromboembolism occurred.
Because of the fragility of enlarged ovaries severe cases, abdominal and pelvic examination should be done very carefully. If conception results, rapid progression of a severe form of the syndrome may occur. To minimize the risks associated with occasional abnormal ovarian enlargement associated with the lowest dose of Clomid therapy consistent with the expected clinical results should be used. Maximum expansion of the ovary, whether physiologic or abnormal, may not occur until a few days after discontinuation of the recommended dose of Clomid. In some patients with polycystic ovary syndrome who are particularly sensitive to gonadotropin may have an exaggerated response to normal doses of Clomid. Therefore, patients with polycystic ovary syndrome should be initiated at the lowest recommended dose and shortest duration of treatment of the first cycle of treatment.

There is other side effects from clomid, we can inform to our friend becarefull if use clomid

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